Papers describing a high-efficient detection of blood-circulating cancer cells may fill the gap of the unknown factors involved in metastasis.
References:
Scripps Research Institute. "New 'biopsy in a blood test' to detect cancer." ScienceDaily, 2 Feb. 2012. Web. 3 Feb.
Journal References:
Jorge Nieva, et al, High-- imaging of circulating tumor cells and associated cellular events in non-small cell lung cancer patients: a longitudinal analysis. Physical Biology, Feb 3, 2012
Dena Marrinucci1, et al, Fluid biopsy in patients with metastatic prostate, pancreatic and breast cancers. Physical Biology, Feb 3, 2012
Daniel C Lazar, et al, Cytometric comparisons between circulating tumor cells from prostate cancer patients and the prostate-tumor-derived LNCaP cell line. Physical Biology, Feb 3, 2012
Edward H Cho, et al, Characterization of circulating tumor cell aggregates identified in patients with epithelial tumors. Physical Biology, Feb 3, 2012
Marco Wendel, et al, Fluid biopsy for Circulating Tumor Cell identification in Patients with early and late stage Non-Small Cell Lung Cancer; a glimpse into lung cancer biology. Physical Biology, Feb 3, 2012
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